Chem. [ad. L. substituens, -entem, pr. pple. of substituĕre to SUBSTITUTE.] An atom or group of atoms taking the place of another atom or group in a compound.
1895–6. Proc. Chem. Soc., 51. The influence of ortho-substituents in preventing alkylation of the carboxyl group.
1905. Brit. Med. Jrnl., 27 May, 1144. A substance having the structure of cinnamic acid, with a hydroxyl (OH) substituent.
