To beat thoroughly.
1848. In the second hand of the third game, I made high, low, and game, and skunked him, outright, again.Durivage and Burnham, Stray Subjects, p. 135.
1853. A severe defeat at the game of draughts was formerly, and, probably, is now, termed a skunk. The man was skunked.S. A. Hammett (Philip Paxton), A Stray Yankee in Texas, p. 349.
1890. I never told you boys how I got skunked once out of a good claim did I?Haskins, Argonauts of California, p. 250.