Hired space for a single person in a business office.
1870. Many of the operators, as well as the smaller brokers who act principally for other houses, and are styled 1-32 and 1-64 men, have simply desk-room.James K. Medbery, Men and Mysteries of Wall Street, p. 117 (Boston).
1910. Dont you lose time by living in Jersey? Not much, answered the Wall Street man. I have desk room on a ferryboat.Louisville Courier-Journal, May.