Hardened, callous.
1819. One, more bold than the rest, with calloused sensibilities, comes forth in the Salem Register.Mass. Spy, March 24.
1850. When she saw, on the back and shoulders of the child, great welts and calloused spots, ineffaceable marks of the system under which she had grown up thus far, her heart became pitiful within her.Mrs. Stowe, Uncle Toms Cabin, ch. xx. (N.E.D.)