subs. (old).Perplexity; commotion: whence TOSTICATED = (1) restless, worried; and (2) intoxicated: also TOSSICATED. See TOSS, verb.
1712. SWIFT, The Journal to Stella, 17 June, xlviii. I have been so TOSTICATED about since my last, that I could not go on in my journal manner.
1748. RICHARDSON, Clarissa, III. lxviii. I want those TOSTICATIONS (thou seest how women and womens words fill my mind) to be over that I may sit down quietly, and reflect.