v. Obs. rare. [f. TREPAN v.1 + -IZE.] = TREPAN v.1

1

1601.  Holland, Pliny, XVII. xxvii. I. 545. Even their bones also use to be trepanized and bored through as well as ours.

2

1684.  Contempl. St. Man, I. v. (1699), 47. Some have been cured by tripanizing the Scull, or drawing Bones from it.

3