a. [f. TRANS- 3 + ISTHMUS: cf. isthmian.] Crossing or extending across an isthmus, esp. the Isthmus of Panama.
1855. Daily Picayune, 25 Feb., 1/4. The ports of Cuba lie too directly in the path of our domestic and trans-isthmian trade to render an inimical policy on the part of its Government desirable to us.
1869. Guardian, 16 Sept., 4/1. It is announced that 90 miles have been graded of the Trans-isthmian Railway on the Spanish Honduras route.
1885. Grover Cleveland, Ann. Message to Congress U.S.A., Dec. Our interests in any transisthmian route which may be opened.
1902. Q. Rev., Oct., 674. The Key to any possible trans-isthmian canal.
