used as combining form of TOXIN (cf. TOXI-) or instead of TOXICO-, in recent scientific terms, chiefly of pathology or physiological chemistry. Toxo-infectious a., involving infection by a toxin: = toxi-infectious (TOXI-). Toxopeptone, (a) a poisonous substance, of the nature of a peptone, found in cultures of cholera bacillus (Cent. Dict. Suppl.); (b) = PEPTOTOXIN. Toxophil a. [Gr. -φιλος loving], having affinity for a toxin. Toxophore, Toxophoric, Toxophorous adjs. [Gr. -φορος bearing, carrying], poison-bearing; applied to a particular group of atoms in the molecule of a toxin to which its toxic properties are due. Toxophylaxin [Gr. φύλαξ guard, protector], Toxosozin [Gr. σώζειν to save], names for defensive proteins or antitoxins (see quots.). Toxoprotein, a toxic protein, or mixture of a toxin and a protein.
1907. Med. Record, 17 Aug., 279. The original cause of the lack of coagulation may be *toxoinfectious, or due to marked congestion.
1896. Allbutt’s Syst. Med., I. 526. Scholl, growing the vibrio, in eggs, obtained a *toxo-peptone.
1902. Vaughan & Novy, Cellular Toxins (ed. 4), 182. The body cells must possess *toxophil side chains. By this we mean that … there are groups of atoms which may combine with bacterial toxins.
1900. Lancet, 18 Aug., 528/1. The *toxophore group of the toxin molecule being much less stable than the haptophore group was much more easily destroyed.
1903. Brit. Med. Jrnl., 21 March, 654. The other atomic group is toxophore, namely, is the cause of the specific toxic action. Ibid. (1902), 29 March, 785. The toxin molecule … must possess a second group which he [Ehrlich] calls the *toxophoric group. Ibid. (1904), 10 Sept., 574. Although the toxophoric group may be similar, the haptophor is dissimilar.
1902. Encycl. Brit., XXVI. 65/1. In the molecule of toxin there are at least two chief atom groups—one, the ‘haptophorous,’ by which the toxin molecule is attached to the cell protoplasm; and the other the *‘toxophorous,’ which has a ferment-like action on the living molecule, producing a disturbance which results in the toxic symptoms.
1899. Syd. Soc. Lex., *Toxophylaxin, a defensive proteid produced in the body of an animal which has acquired immunity for a given infectious disease, and which has the power of rendering inert the toxic products of the pathogenic micro-organisms to which the condition was due.
1896. Allbutt’s Syst. Med., I. 523. The *toxo-proteins in reality are mixtures of albuminous, proteid, or albuminoid bodies with the true toxins.
1899. Syd. Soc. Lex., *Toxosozin, a defensive proteid found in the body of a normal animal which has the power of protecting itself to a greater or less degree against micro-organisms and their products.
