a. Obs. rare. [f. med.L. subtīliāt-, pa. ppl. stem of subtīliāre to SUBTILIATE + -IVE. Cf. It. sottigliativo.] Having the property of thinning, rarefying, dissolving.
c. 1425. trans. Ardernes Treat. Fistula, etc. 89. Þis alkenet is subtiliatyue and resolutyue without mordicacion.
1528. Paynell, Salernes Regim., 4. Whey is subtiliative washyng & lewsynge.
1543. Traheron, trans. Vigos Surg., III. xv. 106 b/2. The medicines must be subtiliatiue and liquide.