a. Obs. [ad. obs. F. substantifique, ad. med.L. substantificus, f. L. substantia SUBSTANCE: see -FIC.] Producing substance.

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1634.  T. Johnson, trans. Parey’s Chirurg., III. xviii. 109. Men … have need of a great quantitie of bloud for the repairing of so many spirits, & the substantificke moisture.

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1653.  Urquhart, Rabelais, I. xix. The substantifick quality of the elementary complexion, which is intronificated in the terrestreity of their quidditative nature.

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  So Substantifical a., whence † Substantifically adv.

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1651.  J. F[reake], Agrippa’s Occ. Philos., 191. There are six substantificall qualities in the Elements, viz. Sharpness, Thinness, Motion, and the contrary to these.

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1657.  B[enjamin] W[elles], trans. Bauderon’s Expert Phisic., xvii. 110. Moyst meat that is substantifically moyst is good for all Feavers.

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