a. Obs. [ad. obs. F. substantifique, ad. med.L. substantificus, f. L. substantia SUBSTANCE: see -FIC.] Producing substance.
1634. T. Johnson, trans. Pareys Chirurg., III. xviii. 109. Men have need of a great quantitie of bloud for the repairing of so many spirits, & the substantificke moisture.
1653. Urquhart, Rabelais, I. xix. The substantifick quality of the elementary complexion, which is intronificated in the terrestreity of their quidditative nature.
So Substantifical a., whence † Substantifically adv.
1651. J. F[reake], Agrippas Occ. Philos., 191. There are six substantificall qualities in the Elements, viz. Sharpness, Thinness, Motion, and the contrary to these.
1657. B[enjamin] W[elles], trans. Bauderons Expert Phisic., xvii. 110. Moyst meat that is substantifically moyst is good for all Feavers.