a. and sb. [f. Gr. κερατ- horn + -OSE.]

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  A.  adj. Of a horny substance; applied to the texture of certain sponges.

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1851–9.  Owen, in Man. Sci. Enq., 365. They are divided … into horny or ‘keratose,’ flinty or ‘siliceous’ and limey or ‘calcareous’ sponges.

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  B.  sb. A substance resembling horn forming part of the skeleton of certain sponges.

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1865.  R. Patterson, in Pop. Sci. Rev. April, 306. In the sponges in domestic use it [the skeleton] is principally composed of a substance termed Keratose.

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1877.  Huxley, Anat. Inv. Anim., iii. 117. A skeleton, which consists … of bands and filaments of keratose, and secondly, of silicious spicula.

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  Hence Keratosed a., rendered horny.

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1894.  Lancet, 3 Nov., 1025. The distinguishing mark between a coccidium and an invaginated or keratosed cell.

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