v. [f. L. exacerbāt- ppl. stem of exacerbā-re, f. ex- intensive + acerb-us harsh, bitter, grievous.]

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  1.  trans. To increase the smart of (a pain), the virulence of (disease), the bitterness of (feeling, speech, etc.); to embitter, aggravate. Also, to embitter or sour the feelings of (a person); to irritate, provoke.

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1620.  trans. P. Du Moulin’s Anatomie of Arminianisme, 497. Certainly it is a greater thing to heale a few that are deadly wounded, then to exacerbate and make more angry & grieuous the wounds of many.

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1660.  Hist. Wars Scot. under Montrose, App. 206. The Ministers never ceased to exacerbate his misery.

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1755.  in Johnson.

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1818.  Art Preserv. Feet, 11. The radical cause of the complaint is often attributed to that which … merely exacerbates the pain.

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1843.  Poe, Gold Bug, Wks. 1864, I. 56. I thought it prudent not to exacerbate the growing moodiness of his temper.

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1852.  Miss Yonge, Cameos (1877), II. viii. 102. Exacerbated by disappointment … he had let loose his rage and passion.

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1876.  Weiss, Wit, Hum. & Shakes., vii. 243. A woman’s language becomes exacerbated because she is so inadequate to protest by actions.

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  2.  intr. for refl.

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1837.  Penny Cycl., VIII. 410/1. The feverish symptoms disappear or remit soon to recur or exacerbate.

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1837.  Carlyle, Fr. Rev., II. IV. v. The sour doubting humour has had leave to accumulate and exacerbate.

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  Hence Exacerbated ppl. a.

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1730–6.  Bailey (folio), Exacerbated, provoked or vexed, afresh.

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1804.  Miniature, No. I. (1806), I. 6. The ponderous dignity of the Rambler would, with ‘exacerbated’ severity, lament the sad degeneracy of the present day [etc.].

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1853.  Kane, Grinnell Exp., xxxvi. (1856), 326. The disease [scurvy] had come back with renewed and even exacerbated virulence.

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1857.  G. Gilfillan, in Waller & Denham’s Poems, 208. Butler, then a disappointed and exacerbated man, was malignant enough to lampoon him for lunacy.

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