a. [f. Gr. ἐν + δέρμ-α skin + -IC.] That acts on the skin, or by penetrating beneath the skin. Endermic method (see quot. 1831).

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1831.  J. Davies, Man. Mat. Med., 263. He administers it by the endermic method; that is, applied in the form of a salve on a part deprived of the epidermis.

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1875.  H. C. Wood, Therap. (1879), 21. The endermic method is very rarely employed.

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