a. Obs. [ad. L. effrēnāt-us, f. effrēnāre, f. ex out + frēn-um bridle. Cf. F. effréné.] a. Of passions: Unbridled, ungovernable. b. Of drugs: Violent in action.
1561. Abp. Parker, Corr. (1852), 157. Men of effrenate intemperancy.
1657. Tomlinson, Renou’s Disp., 143. Nothing doth so much dehort from … any medicament as its effrenate, prepotent and malign quality.
Hence Effrenated ppl. a., unbridled, unruly.
1586. J. Hooker, Girald. Irel., in Holinshed, II. 144/1. Let vs returne to the historie of this effere and effrenated nation.
