Chem. [see -IN.] The bitter principle of colocynth, resembling a semi-transparent resin, and readily soluble in alcohol.

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1830.  Lindley, Nat. Syst. Bot., 193.

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1840.  Henry, Elem. Chem., II. 333. It contains the bitterness of the colocynth, and appears … to be a particular principle, for which he proposes the name of colocyntine.

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1876.  Bartholow, Mat. Med. (1879), 481. Colocynthine is a very powerful cathartic.

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