Path. Rarely cirrhose. [mod.L., f. Gr. κιρρ-ός orange-tawny, after words in -ωσις, -osis; cf. F. cirrhose.] A name given by Laennec to a disease of the liver, occurring most frequently in spirit-drinkers, and consisting in chronic interstitial hepatitis, with atrophy of the cells and increase of connective tissue. Called also Hob-nailed or Gin-drinker’s Liver. Subsequently extended to interstitial inflammation of the kidneys, lungs, and other organs.

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  The name referred to the presence of yellowish granules, which Laennec supposed to be a deposit of new matter; but these were subsequently shown to be the isolated and bile-tinged acini of the liver itself. In cirrhosis of the other organs there is, of course, no yellow color.

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1839–47.  Todd, Cycl. Anat., III. 188/2. The form of atrophy of the liver … named by Laennec cirrhosis. Ibid., III. 642/1. Patients who die of … cirrhose of the liver.

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1854.  W. Stokes, Diseases of Heart, 461. That disease to which Dr. Corrigan has [1838], given the name of cirrhosis of the lung.

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1860.  Mayne, Expos. Lex., Cirrhosis.… Name proposed for granulated, or tuberculated kidney.

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1872.  T. G. Thomas, Dis. Women, 283. This constitutes a true cirrhosis of the uterus.

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1880.  Med. Temp. Jrnl., Oct., 6. Alcoholic cirrhosis constitutes one species distinct from all the other.

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