[a. Sp. cascarilla, dim. of cascara rind, bark. In F. cascarille.] The bitter aromatic bark of the plant Croton eleuteria, used as a tonic. Also called cascarilla bark.

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1686.  Lond. Gaz., No. 2186/1. 200 thousand pounds of the Bark of Trees, called Cascarilla.

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1759.  B. Stillingfl., trans. Beyerstein’s Physic, in Misc. Tracts (1762), 210. They use the cascarilla, which is certainly a very good medicine in shiverings.

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1826.  Good, Bk. Nat. (1834), I. 191. The cascarilla bark and castor oil are obtained from plants poisonous in some part or other.

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1870.  Yeats, Nat. Hist. Comm., 234.

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  Hence Cascarillin, a bitter substance (C12 H18 O4) obtained from cascarilla bark.

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1875.  H. C. Wood, Therap. (1879), 83. Cascarillin, a neutral, bitter, crystallizable principle.

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