[ad. L. vīrulentia: see next and -ENCE. So OF. and F. virulence.]

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  1.  Extreme acrimony or bitterness of temper or speech; violent malignity or rancor.

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1663.  Jer. Taylor, Fun. Serm. Bramhall, Wks. 1831, IV. vii. 75. It was also such honor, that it is greater than the virulence of tongues, which his worthiness and their envy had armed against him.

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1696.  Tate & Brady, Ps. cxl. 3. Their sharpen’d Tongue the Serpent’s sting In Virulence exceeds.

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1728.  Young, Love Fame, VI. 150. Our virulence is thrown On others’ fame, thro’ fondness for our own.

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1748.  Richardson, Clarissa (1811), I. iv. 28. My sister, who had treated Mr. Lovelace with virulence, came into me and insulted me as fast as I recovered.

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1796.  Bp. Watson, Apol. Bible, 322. I have been frequently shocked at the virulence of your zeal.

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1838.  Dickens, Nickleby, xxi. The ill will of Miss Knag had lost nothing of its virulence.

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1867.  Smiles, Huguenots Eng., xi. (1880), 194. The persecution … was carried on with increased virulence, until resistance almost disappeared.

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  b.  An instance of this.

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a. 1774.  Tucker, Lt. Nat. (1834), II. 295. The leaders, however they may sometimes encourage these virulences to serve a turn, do not enter into the same sentiments themselves.

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  2.  The property or quality of being physically virulent or full of virus; extreme poisonousness or venomousness; malignity or violence (of disease).

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1748.  Anson’s Voy., I. x. 106. A general dejection prevailed amongst us, which added much to the virulence of the disease.

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1789.  W. Buchan, Dom. Med. (1790), 519. I have frequently known the disease return with all its virulence after a course of goat-whey.

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1815.  J. Smith, Panorama Sci. & Art, II. 48. The wind is salubrious, stopping infection, and removing the virulence of distemper.

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1834.  Mrs. Somerville, Connex. Phys. Sci., xxvii. 283. Venomous snakes … decrease … in the virulence of their poison with decrease of temperature.

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1878.  H. M. Stanley, Dark Cont., II. xii. 361. The itch disease was rabid;… about a dozen of the men were fearful objects of its virulence.

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  attrib.  1896.  Allbutt’s Syst. Med., I. 721. Whether … the virulence test is satisfactory and exclusive is a doubtful matter.

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